Live Topical Biotherapeutics for the Treatment of Inflammatory Skin Disorders

An evolutionary approach to restoring health

AOBiome Therapeutics is a late stage therapeutics company addressing a broad range of inflammatory skin conditions by harnessing a single strain of class defining Ammonia Oxidizing Bacteria (AOB), whose presence on the skin has been eliminated through modern living.

RESTORING IMMUNE FUNCTIONALITY

Ammonia Oxidizing Bacteria may serve to restore proper immune response through the down regulation of IL-4, IL-5, IL-13 and IL-31. Such markers are associated with inappropriate inflammatory response in several diseases including the pruritus (itch) pathway.

AOBiome currently has multiple
Phase 2 clinical programs

AOBiome currently has Phase 2 clinical programs in acne, eczema and rosacea.

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Committed to transforming & improving human health

We believe that the restoration of the symbiotic relationship between bacteria and humans
will have a profound impact on human health.

Clinical Trials

Science

Manufacturing

About

In the News

January 30, 2024 · Osaka, Japan

AOBiome and Maruho have entered into an Exclusive License Agreement for a Novel Therapeutic for the treatment of Atopic Dermatitis in Japan

January 5, 2024 · Cambridge, MA

AOB Pharma and Maruho enter into an Exclusive License Agreement for AOB Pharma’s Topical Biologic B244 for the Treatment of Inflammatory Indications including Atopic Dermatitis in Japan

May 16, 2023 · Cambridge, MA

AOBiome announces the publication of positive Phase 2b results in The Lancet’s eClinicalMedicine for B244 in the treatment of mild-to-moderate atopic dermatitis and moderate-to-severe pruritus

April 6, 2023 · Cambridge, MA

AOBiome Therapeutics Granted Composition of Matter Patent for its Clinical Candidate B244